Howard
Payne Course Numbers
Biochemistry 1: CHE 4439
Includes 3 hours of lecture and 4 hours of laboratory per week
Biochemistry 2: CHE 4449
Includes 3 hours of lecture and 4 hours of laboratory per week
GOALS AND OBJECTIVES
This course is intended for the student who is in a pre-professional curriculum or is majoring in chemistry or biology. It is designed to acquaint the student with the major classes of compounds which are important biochemically. After a careful consideration of their structure, physical properties, and chemical properties, their role in living systems will be studied. The course will emphasize human and plant biochemistry in that order of priority. Thus, the goals of the course are:
1. To become intimately familiar with the composition, structure, physical properties, and chemical characteristics of the major classes of biochemical compounds (i. e., carbohydrates lipids, proteins, enzymes, and nucleic acids).
2. To be able to relate the information and concepts described in the above objective to biochemical processes-metabolism, photosynthesis, biosynthesis, etc.
3. To become proficient in simple laboratory techniques used to study biochemical systems.
4. To develop the ability to design experiments which will yield answers to critical questions that must be answered in order to understand the sacred quality known as life.
ASSESSMENT
This course will be assessed using an end of course standardized exam published by the American Chemical Society at the end of the second semester.
FIRST SEMESTER TOPICAL OUTLINE
1. Introduction and Proteins
Biochemistry An Evolving Science
Protein Composition and Structure
Exploring Proteins and Proteomes
2. DNA, RNA, Hemoglobin and Enxymes
DNA and RNA
Hemoglobin
Enzymes
3. Catalytic and regulatory strategies
Catalytic Strategies
Regulatory Strategies
4. Carbohydrates and lipids
Carbohydrates
Lipids and Cell Membranes
Membrane Pumps
5. Pathways
Signal transduction Pathways
Student Laboratory Presentations: